A morphological and immunohistochemical investigation of guinea pig skin after the introduction of substance P and VIP.
نویسندگان
چکیده
The aim of this study was to examine a morphological picture of guinea pig skin that had been injected with neuropeptides (NPS)(2)- substance P (SP) and guinea pig vasoactive intestinal peptide (VIP) - to elucidate their local influence. Routine histological stainings were performed, together with immunohistochemical reactions for T cells and for macrophages. In the deeper layers of the skin, T cell and macrophagic infiltrations were observed. The intensity of these changes was greater 24 hours after injections than that observed at the third hour of the experiment.
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ورودعنوان ژورنال:
- Cellular & molecular biology letters
دوره 8 1 شماره
صفحات -
تاریخ انتشار 2003